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Ubiquitin-Protein Ligases

  • CELL AND ORGANELLE STRUCTURE AND ASSEMBLY
    The Hsp70 and TRiC/CCT Chaperone Systems Cooperate In Vivo To Assemble the Von Hippel-Lindau Tumor Suppressor Complex
    Mark W. Melville, Amie J. McClellan, Anne S. Meyer, Andre Darveau, Judith Frydman
  • CELL GROWTH AND DEVELOPMENT
    The Grb10/Nedd4 Complex Regulates Ligand-Induced Ubiquitination and Stability of the Insulin-Like Growth Factor I Receptor
    Andrea Vecchione, Adriano Marchese, Pauline Henry, Daniela Rotin, Andrea Morrione
  • GENE EXPRESSION
    von Hippel-Lindau Protein-Mediated Repression of Tumor Necrosis Factor Alpha Translation Revealed through Use of cDNA Arrays
    Stefanie Galbán, Jinshui Fan, Jennifer L. Martindale, Chris Cheadle, Bryan Hoffman, Michael P. Woods, Gretchen Temeles, Jürgen Brieger, Jochen Decker, Myriam Gorospe
  • NUCLEOCYTOPLASMIC COMMUNICATION
    Oxygen-Dependent Ubiquitination and Degradation of Hypoxia-Inducible Factor Requires Nuclear-Cytoplasmic Trafficking of the von Hippel-Lindau Tumor Suppressor Protein
    Isabelle Groulx, Stephen Lee
  • CELL GROWTH AND DEVELOPMENT
    Transferable Domain in the G1 Cyclin Cln2 Sufficient To Switch Degradation of Sic1 from the E3 Ubiquitin Ligase SCFCdc4 to SCFGrr1
    Catherine Berset, Peter Griac, Rebecca Tempel, Janna La Rue, Curt Wittenberg, Stefan Lanker
  • TRANSCRIPTIONAL REGULATION
    The E2 Ubiquitin Conjugase Rad6 Is Required for the ArgR/Mcm1 Repression of ARG1 Transcription
    Suzanne D. Turner, Andrea R. Ricci, Helen Petropoulos, Julie Genereaux, Ilona S. Skerjanc, Christopher J. Brandl
  • CELL GROWTH AND DEVELOPMENT
    APS Facilitates c-Cbl Tyrosine Phosphorylation and GLUT4 Translocation in Response to Insulin in 3T3-L1 Adipocytes
    Jun Liu, Akiko Kimura, Christian A. Baumann, Alan R. Saltiel
  • TRANSCRIPTIONAL REGULATION
    Carboxyl-Terminal Transactivation Activity of Hypoxia-Inducible Factor 1α Is Governed by a von Hippel-Lindau Protein-Independent, Hydroxylation-Regulated Association with p300/CBP
    Nianli Sang, Jie Fang, Vickram Srinivas, Irene Leshchinsky, Jaime Caro
  • CELL GROWTH AND DEVELOPMENT
    Diverse Effects of Mutations in Exon II of the von Hippel-Lindau (VHL) Tumor Suppressor Gene on the Interaction of pVHL with the Cytosolic Chaperonin and pVHL-Dependent Ubiquitin Ligase Activity
    William J. Hansen, Michael Ohh, Javid Moslehi, Keiichi Kondo, William G. Kaelin, William J. Welch
  • CELL GROWTH AND DEVELOPMENT
    Obligate Roles for p16Ink4a and p19Arf-p53 in the Suppression of Murine Pancreatic Neoplasia
    Nabeel Bardeesy, Jeffrey Morgan, Manisha Sinha, Sabina Signoretti, Shefali Srivastava, Massimo Loda, Glenn Merlino, Ronald A. DePinho

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